CBD Therapeutic Benefits
The World Health Organization published a report on CBD in November of 2017. Below is an overview of which CBD may have therapeutic benefits.
|Alzheimer’s disease||Anti-inflammatory, antioxidant, antiapoptotic in vitro and in vivo models
of Aβ-evoked neuro-inflammatory and neurodegenerative responses.
|Parkinson’s disease||Attenuation of the dopaminergic impairment in vivo; neuroprotection; improvement of psychiatric rating and reduction of agitation, nightmare
and aggressive behavior in patients.
|Multiple sclerosis||Improved signs of EAE in mice, ant-inflammatory and immunomodulatory
|Huntington’s disease||Neuroprotective and antioxidant in mice transgenic models; no significant
clinically important differences in patients.
|Hypoxia-ischemia injury||Short term neuroprotective effects; inhibition of excitotoxicity, oxidative
stress and inflammation in vitro and rodent models.
|Pain||Analgesic effect in patients with neuropathic pain resistant to other
|Psychosis||Attenuation of the behavioral and glial changes in animal models of
schizophrenia; anti-psychotic properties on ketamine-induced symptoms
|Anxiety||Reduction of muscular tension, restlessness, fatigue, problems in concentration, improvement of social interactions in rodent models of
anxiety and stress; reduced social anxiety in patients.
|Depression||Anti-depressant effect in a genetic rodent model of depression.|
|Cancer||Antiproliferative and anti-invasive actions in a large range of cancer types;
induction of autophagy-mediated cancer cell death; chemopreventive effects.
|Nausea||Suppression of nausea and conditioned gaping in rats|
|Inflammatory diseases||Ant inflammatory properties in several in vitro and in vivo models;
inhibition of inflammatory cytokines and pathways.
|Rheumatoid arthritis||Inhibition of TNF-α in an animal model|
|Infection||Activity against methicillin-resistant Staphylococcus aureus|
|Inflammatory bowel and Crohn’s diseases||Inhibition of macrophage recruitment and TNF-α secretion in vivo and ex vivo reduces disease activity index in Crohn’s patients.|
|Cardiovascular diseases||Reduced infarct size through antioxidant and anti-inflammatory
properties in vitro and in vivo.
|Diabetic complications||Attenuation of fibrosis and myocardial dysfunction|
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